Journal of Health, Technology and Science (JHTS)
Journal of Health, Technology and Science (JHTS) is a scientific journal of Bina Mandiri University Gorontalo that presents original articles containing knowledge and information related to the development of the latest research in the fields of Health, Technology and Science. This journal is published four times a year (1 Volume). Manuscripts published in the JHTS journal cover areas relevant to research findings, case studies, or theoretical discussions.
OVERVIEW OF LOCAL FOOD CONSUMPTION PATTERNS AMONG TODDLERS AT THE HOUSEHOLD LEVEL IN THE VILLAGE OF ULANTHA BONE BOLANGO REGENCY
This study aims to determine the pattern of local food consumption among toddlers at the household level in Ulanta Village, Bone Bolango Regency. The type of research used is quantitative descriptive with a cross-sectional approach. The research sample consisted of 30 respondents who were housewives with toddlers, selected using purposive sampling techniques. Data collection was conducted through questionnaires and direct interviews, then analyzed descriptively to obtain frequency distributions and percentages. The results showed that most people still consume local foods such as bananas (90%), local fish (90%), fruits (83.3%), and vegetables (76.7%), while the consumption of cassava (46.7%) and sago (26.7%) is relatively low. Most respondents had good knowledge about the benefits of local foods (53.1%) and considered local foods to be easily available and affordable. A total of 75% of respondents had good eating habits. The conclusion of this study is that local foods play an important role in meeting the nutritional needs of toddlers and household food security, but education and processing innovations are needed to maintain local food consumption.
Local Food, Consumption Patterns, Toddlers, Households, Nutrition.
Hak Cipta (c) 2025 Rizkadayatrina A.I.Lamase
PENGARUH POLA ASUH MAKANAN DAN POLA ASUH KESEHATAN TERHADAP STATUS GIZIANAK BALITA DI KECAMATAN ATINGGOLA KABUPATEN GORONTALO UTARA
Penelitian ini bertujuan untuk mengetahui pengaruh Pola Asuh Makanan dan Pola Asuh Kesehatan terhadap status gizi anak balita di Kecamatan Atinggola Kabupaten Gorontalo Utara. Penelitian ini menggunakan observational analitik dengan pendekatan kuantitatif. Pada penelitian ini jumlah populasi yang di dapatkan di wilayah puskesmas Atinggola Kabupaten Gorontalo Utara berjumlah 118 balita dengan menggunakan rumus Slovin didapatkan jumlah sampel sebanyak 21 orang. Hasil dari penelitian ini menunjukkan status gizi dengan kategori baik sebanyak 15 balita (71,4 %), buruk sebanyak 2 balita (9,5 %), pola asuh makan dengan kategori baik sebanyak 12 orang (57,1 %) dan cukup sebanyak 9 orang (42,9%), pola asuh kesehatan dengan kategori baik sebanyak 19 orang (90,4 %), cukup sebanyak 1 orang (4,8%) dan kurang sebanyak 1 orang (4,8%), status gizi balita dengan kategori baik sebanyak 15 balita (71,4 %), gizi kurang sebanyak 3 balita (14,2 %) dan gizi buruk sebanyak 2 balita (9,5%). Hasil uji chis-quare diperoleh untuk variabel pola asuh makan nilai p = 0,023 dan untuk pola asuh kesehatan diperoleh nilai p = 0,02 kecil dari nilai α (0,05) sehingga dapat disimpulkan terdapat terdapat pengaruh pola asuh makan dan pola asuh kesehatan terhadap status gizi anak balita di Kecamatan Atinggola Kabupaten Gorontalo Utara Tahun 2022.
pola asuh makan, pola asuh kesehatan, status gizi.
Hak Cipta (c) 2025 Sri Masyita Djailani, Yolan H. Dunggio, Arpin
LAVENDER AROMATHERAPY WAX (Lavandula angustifolia) FORMULATION WITH OIL PURIFICATION BASE USED COOKING OIL AS A REPELLENT
Malaria masih menjadi masalah kesehatan di Indonesia, termasuk di Provinsi Gorontalo dengan jumlah kasus tercatat sebanyak 1.581 kasus. Upaya pencegahan dilakukan melalui pengembangan repelan alami yang aman dan ramah lingkungan dengan menggunakan lavender. Penelitian ini bertujuan untuk mengetahui evaluasi dan aktivitas formulasi lilin aromaterapi lavender ( Lavandula angustifolia ) dengan basis pemurnian minyak jelantah sebagai repelan terhadap nyamuk Anopheles vagus. Metode dalam penelitian ini menggunakan metode eksperimen dengan empat formula yaitu minyak atsiri lavender F0 (0%), F1 (15%), F2 (20%), dan F3 (25%). Evaluasi meliputi uji organoleptik, lama bakar, titik leleh, uji hedonik, dan aktivitas repelan terhadap nyamuk Anopheles vagus. Data dianalisis secara statistik menggunakan uji One Way ANOVA . Hasil penelitian menunjukkan bahwa keseluruhan formula lilin aromaterapi berbentuk padat, berwarna ungu merata, bertekstur halus, dengan lama bakar optimal dan titik leleh 50–58°C. Uji hedonik menunjukkan bahwa F1 dan F2 paling disukai panelis, sementara F3 terlalu menyengat dan F0 kurang menarik. Semua formula dengan ekstrak lavender memiliki aktivitas repelan terhadap nyamuk Anopheles vagus. Uji statistik tidak menunjukkan perbedaan signifikan dalam waktu pembakaran dan titik leleh antar formula. Disimpulkan bahwa lilin aromaterapi lavender berbahan dasar minyak goreng bekas berpotensi sebagai repelan dengan daya terima aroma terbaik pada konsentrasi 15–25%.
Lilin Aromaterapi, Lavender, Minyak Jelantah, Repellent, Anopheles Vagus
Hak Cipta (c) 2025 Siti Nurul H. Adam, Srimuliani Arbie, Sucia Pratiwi Tampoy
TRENDS AND DEVELOPMENTS IN MOLECULAR DIAGNOSTICS FOR ANTIBIOTIC RESISTANCE DETECTION
Antimicrobial Resistance (AMR) poses a global threat, necessitating a shift from slow culture-based methods (24–48 hours) to rapid molecular diagnostics to ensure timely targeted therapy. Methodology: This study employed a Systematic Literature Review (SLR) and bibliometric analysis of 10,776 Scopus-indexed articles (up to 2024) using the PRISMA protocol and VOSviewer for network visualization. Publications peaked in 2024, with the United States and China leading global contributions. Thematic analysis reveals a transition from basic genetic studies to advanced technologies like NGS, multiplex PCR, CRISPR-based systems, and microfluidic biosensors. Key markers include carbapenemase (blaNDM, blaKPC), colistin resistance (mcr-1), and ESBLs. Emerging trends emphasize AI integration and decentralized Point-of-Care (POC) testing. Conclusion: Molecular diagnostics are vital for Antimicrobial Stewardship. Despite technological leaps, clinical standardization and costs remain significant barriers. This mapping provides a strategic roadmap for enhancing global resistance surveillance and precision diagnostics.
Antimicrobial resistance; Molecular diagnostics; PCR; Next-generation sequencing; CRISPR-Cas; Point-of-care testing.
Hak Cipta (c) 2025 SINTYA AGY NURAISAH ISANG
THE EFFECT OF PHARMACEUTICAL EDUCATION ON PUBLIC KNOWLEDGE AND ATTITUDES TOWARDS THE USE OF PRESCRIPTION DRUGS IN TOYIDITO VILLAGE, PULUBALA DISTRICT, GORONTALO REGENCY
The lack of public knowledge regarding the use of prescription drugs is one of the factors contributing to the high rate of non-prescription drug use in the community. This study aims to determine the effect of pharmaceutical education on public knowledge and attitudes towards the use of prescription drugs in Toyidito Village, Pulubala District, Gorontalo Regency. The research method used was a descriptive, quantitative survey design. Sampling was conducted using purposive sampling with a total of 100 respondents. The research instrument consisted of a questionnaire that had been tested for validity and reliability. Data analysis was performed univariately and bivariately using the Chi-Square test to assess relationships among variables. The study found that respondents' knowledge levels after education fell into the categories of good (32%), sufficient (25%), and poor (43%). Regarding attitudes, respondents were distributed across good (73%), satisfactory (17%), and poor (10%). Statistical tests indicated a significant effect of pharmaceutical education on improvements in public knowledge and attitudes (p-value = 0.030). Thus, pharmaceutical education was proven effective in enhancing understanding and shaping a positive attitude among the public towards the rational and safe use of prescription drugs. Conclusion: Pharmaceutical education has been shown to significantly improve the public's knowledge and attitudes regarding the use of prescription drugs. The majority of the public showed increased understanding and positive attitudes after receiving education, indicating that pharmaceutical education activities need to be carried out continuously to support safer and wiser use of prescription drugs.
Pharmaceutical Education, Knowledge, Attitude, Prescription Drugs, Public
Hak Cipta (c) 2025 Purnama Abdullah, oktarina mahanggi, ahmad husain palii
GAMBARAN KADAR HbA1c PADA PENDERITA DIABETES MELITUS DI PUSKESMAS DUNGALIYO
Diabetes Melitus merupakan penyakit gangguan metabolisme yang di tandai oleh kenaikan gula darah akibat penurunan sekresi insulin oleh sel beta pankreas dan ganguan fungsi insulin (resistensi insulin). Dengan mengukur glikohemoglobin (HbA1C) dapat diketahui berapa besar persentasi zat warna sel darah merah (hemoglobin) yang mengandung glukosa. Penlitian ini bertujuan untuk mengetahui Gambaran Kadar HbA1c Pada Penderita Diabetes Melitus di Puskesmas Dungaliyo. Metode dalam penelitian ini menggunakan pendekatan kuantitatif yang bersifat deskriptif. Jenis data yang digunakan adalah data primer berupa hasil penelitian pemeriksaan kadar HbA1c pada penderita diabetes melitus dan data sekunder berupa data-data dari kuesioner dan catatan rekam medic terhadap pasien diabetes mellitus di Puskesmas Dungaliyo. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik accidental sampling, dengan jumlah sampel 39 orang. Hasil penelitian menunjukkan bahwa dari 39 sampel yang di periksa kadar HbA1c pada penderita diabetes melitus, terdapat 35 sampel atau 89,7% yang kadar HbA1c nya abnormal. Sedangkan yang kadar HbA1c nya normal sebanyak 4 sampel atau 10,3%. Adapun saran yang disampaikan pada penderita Diabetes Mellitus yaitu dianjurkan supaya rutin kontrol kedokter dan memeriksakan kesehatan ke laboratorium dan lebih memerhatikan pola hidup yang baik sehingga mendapatkan pengendalian Diabetes Melitus yang baik.
Hak Cipta (c) 2023 Wilan Hamzah, Niluh Arwati, Mindy Eka Astuti
IDENTIFICATION OF MERCURY AND HYDROQUINONE CONTENT IN HANDBODY PRODUCTS CIRCULATING IN GORONTALO CITY
This study aims to determine the presence of dangerous chemical compounds, namely mercury and hydroquinone in hand body preparations circulating in Gorontalo City. The method used in this study uses descriptive research with an observational approach and qualitative laboratory tests. From the research results, 12 samples were tested for mercury (using NaOH and KI), 4 positive samples contained mercury and 8 negative samples contained mercury. 4 samples were marked by a yellow color change in the NaOH solution and a red color in KI solution and the 8 negative samples did not change color so that these samples did not contain harmful chemicals in the handbody. From the results of the 12 samples that were subjected to the hydroquinone test (using FeCl3) the results obtained were 2 positive samples containing hydroquinone and 10 samples not containing hydroquinone. The 2 positive samples were marked by a change in green color and had precipitate in the sample, whereas in the 10 samples the results obtained had no color change and had no precipitate in the sample tested.
Hak Cipta (c) 2023 Aprilia Putri Efendy, Adnan Malaha, Alfian S. Abas
DESCRIPTION OF THE IMPLEMENTATION OF DRUG DISTRIBUTION IN REGIONAL GENERAL HOSPITAL PHARMACY INSTALLATIONS OTANAHA GORONTALO CITY
This study aims to describe the drug distribution system in the Pharmacy Installation of the Otanaha Hospital, Gorontalo City, which has been carried out in accordance with applicable standard procedures. This research method uses a descriptive research type with qualitative approach. The research was carried out on 4 informants who directly related to the drug distribution process at the Hospital Pharmacy Installation Gorontalo City Otanaha, namely the Head of IFRS, Pharmacist in charge of the warehouse, Pharmacists in charge of pharmacies, and nurses by conducting interviews directly to informants with the aim of digging up information related to the drug distribution process. The results showed that the distribution of drugs in the Pharmacy Installation of the Otanaha Hospital, Gorontalo City, was mostly in accordance with the hospital pharmaceutical service standards based on the Minister of Health Regulation number 72 of 2016, but for the distribution service system there were still things that needed to be implemented, such as the Pharmacy Installation of the Otanaha Hospital, Gorontalo City had not implemented the distribution system is a decentralized method, the Floor Stock method and the UDD method because space is not yet available and staff is lacking.
Drug distribution, IFRS, management of pharmaceutical supplies
Hak Cipta (c) 2023 Riska Mooduto, Rini Daud Supu, Adnan Malaha
ANALISIS POLA WAKTU KERJA PRODUKTIF PERAWAT DI UNIT RAWAT INAP RSUD PROF. DR. ALOEI SABOE KOTA GORONTALO
Penelitian ini dilakukan di unit rawat inap RSUD Prof. Dr. Aloei Saboe Kota Gorontalo. Jenis penelitian ini merupakan penelitian kuantitatif dengan metode Survei. Peneliti mengumpulkan fakta dan informasi melalui pertanyaan-pertanyaan kepada responden yang mewakili populasi terkait waktu kerja produktif perawat di unit rawat inap RSUD Prof. DR. Aloei Saboe. Metode yang digunakan dalam penelitian yaitu dengan melakukan pengamatan observasi/pengamatan dengan menyebarkan kuisioner yang berisi pertanyaan terkait penggunaan waktu dalam pelaksanaan kegiatan kerja yang akan disebarkan pada para perawat di unit rawat inap RSUD Prof. DR. Aloei Saboe sejumlah 40 orang responden. Hasil penelitian menunjukkan bahwa Kegiatan di unit rawat inap RSUD Prof. Dr. Aloei Saboe terdiri dari keperawatan langsung dan keperawatan tidak langsung dan perawat di unit rawat inap RSUD Prof. DR. Aloei Saboe melakukan pekerjaan secara produktif pada jam dinas dengan proporsi pola waktu produktif sebanyak 373 menit atau setara dengan (6 jam 10 menit) dengan persentasi 85% dari 100% keseluruhan waktu kerja.
Perawat, pola waktu kerja, produktvitas kerja
Hak Cipta (c) 2023 Dea Rahmatia Yunus, Dwi Lassmy Samaritan, Meyrin Kadir
Bakteri Escherichia coli (E. coli) Pada Sarana Air Bersih Sumur Gali Di Kelurahan Hunggaluwa Kecamatan Limboto Kabupaten Gorontalo
Sumur gali merupakan sumber air bersih yang sangat dibutuhkan oleh masyarakat secara umum, sehingga haruslah memenuhi persyaratan baik dari segi fisik, kimia, maupun bakteriologis. Masyarakat di Kelurahan Hunggaluwa menggunakan sumur gali untuk memenuhi kebutuhan mereka terkait air bersih untuk berbagai macam keperluan, baik mencuci, memasak, dan lain-lain. Tujuan dari penelitian ini adalah untuk mengetahui kondisi sumur gali berdasarkan parameter fisik dfan bakteriologis. Diperoleh hasil penelitian bahwa terdapat sumur gali yang terbuat bahan yang kuat, kedap air dan tinggi > 80 cm berjumlah 22 buah (100%). Untuk sumur yang di plester, panjang minimal 1 m dan kemiringan 100 berjumlah 22 buah (100%). Untuk jarak sumur dengan jamban diperoleh bahwa terdapat sumur <11 meter berjumlah 17 buah dan yang >11 meter berjumlah 5 buah. Berdasarkan kandungan bakteri Escherichia Coli (E.Coli), terdapat 2 sumur yang memenuhi syarat, dan 20 sumur tidak memenuhi syarat. Berdasarkan hasil penelitian yang dilakukan oleh peneliti, maka dapat disimpulkan bahwa :Kandungan Bakteri Escherichia Coli (E.Coli) Pada Sarana Air Bersih Sumur Gali (SGL) di Kelurahan Hunggaluwa Lingkungan 5 Kecamatan Limboto. Disimpulkan bahwa sarana air bersih Sumur Gali (SGL) di Kelurahan Hunggaluwa Lingkungan 5 Kecamatan Limboto Kabupaten Gorontalo 91 % tidak memenuhi syarat dan 9% memenuhi syarat.
Hak Cipta (c) 2023 Yanti Mustafa, Rahman Suleman, Sulastri Pua Age; Masri Jasin
DETEKSI FORMALIN PADA TAHU YANG DIJUAL DI PASAR TRADISIONAL KOTA GORONTALO MENGGUNAKAN EKSTRAK UBI JALAR UNGU
Formalin merupakan bahan kimia yang penggunannya dilarang untuk produk makanan. Formalin dengan nama dagangannya yaitu formaldehyde dalam air dengan kadar 30-40%. Kontaminasi formaldehida dalam bahan makanan sangat membahayakan tubuh. Formaldehida dapat menyebabkan kanker saluran pernapasan dan meningkatkan resiko leukimia Penelitian ini bertujuan untuk mengetahui ada dan tidaknya kandungan formalin pada tahu menggunakan ekstrak ubi jalar ungu yang dilakukan dengan menggunakan metode ekstraksi maserasi. Bahan alami yang mengandung antosianin dapat dijadikan sebagai alternatif pengujian formalin. Penelitian ini menggunakan metode penelitian kualitatif dengan menggunakan ekstrak ubi jalar ungu sebagai indikator pemeriksaan karena mengandung antosianin yang mampu mendeteksi adanya kandungan formalin dalam tahu dengan reaksi perubahan warna. antosianin yang bersifat amfoter yang mempunyai kemampuan untuk bereaksi baik dengan pH yang asam maupun basa, jika dalam media yang bersifat asam antosianin akan berwarna merah. Formalin bersifat asam, sehingga apabila antosianin bertemu dengan formalin akan menghasilkan perubahan warna merah yang semakin pekat. Sedangkan apabila pigmen antosianin tidak berubah warna menjadi merah atau tetap pada warna asalnya maka tidak mengandung formalin. Antosianin akan berubah warna seiring dengan perubahan nilai pH Hasil penelitian menunjukkan bahwa 19 sampel tahu yang diuji dinyatakan negatif ditandai dengan tidak terjadinya reaksi perubahan warna menjadi biru kemerahan.
Tahu, Ekstrak Ubi Jalar Ungu, Antosianin.
Hak Cipta (c) 2023 Waridatul Khosidah, Adnan Malaha, Erfan AR Lainjong
This study aims to determine the results of examination of endoparasite worms in beef at the Gorontalo City Slaughterhouse and to determine the factors that influence the presence of endoparasite worms in beef at the Gorontalo City Slaughterhouse. This research method uses a quantitative research approach with the type of research used in this research is descriptive observational research. The population in this study was all sirloin meat in the Gorontalo City Slaughterhouse, amounting to 20. The sample used was 12 with the sampling technique using Accidental Sampling. The results of this study showed that 12 samples were positively infected with endoparasite worms with a percentage (100%). Types of endoparasitic worms found included 2 species of Fasciola hepatica, 1 species of Strongyloides papillosus, 1 species of Paramphistomum, 1 species of Trichostrongylus, 1 species of Bunostomum, 1 species of Cooperia, 1 species of Strongyloides stercoralis, 1 species of Toxocara vitulorum, 1 species of Haemonchus contortus, Oesophagustomum 2 types.
Hak Cipta (c) 2023 Fadhilah Datau, Arpin, Mindy Eka Astuti
DESCRIPTION OF BLOOD GLUCOSE LEVELS IN OBESITY PATIENTS IN PUSKESMAS NORTH CITY
Penelitian ini bertujuan untuk mengetahui kadar glukosa darah pada pasien obesitas di Puskesmas Kota Utara beserta faktor yang mempengaruhinya. Metode pada penelitian ini menggunakan pendekatan kuantitatif yang bersifat deskriptif. Jenis data yang digunakan adalah data primer berupa hasil penelitian kadar glukosa darah pada pasien obesitas dan data sekunder berupa data-data dari literatur, buku, kuesioner, dan buku rekam medik. Teknik pengambilan sampel dalam penelitian ini menggunakan accidental sampling, dengan jumlah sampel sebanyak 29 orang. Hasil penelitian menunjukkan bahwa dari 29 pasien obesitas, terdapat 24 orang atau 82,8% yang kadar glukosa darahnya tidak normal, sedangkan yang kadar glukosa darahnya normal 5 orang atau 17,2%. Faktor yang mempengaruhi kadar glukosa darah pada pasien obesitas adalah : jenis kelamin, umur, pola fisik (Indeks Massa Tubuh/IMT), aktifitas fisik dan pola Makan (jumlah kalori). Saran kepada peneliti berikutnya disarankan untuk meneliti kadar kadar gula darah antara kelompok obesitas dengan non obesitas sebagai pembanding.
Blood Glucose Levels, Obese Patients, Body Mass Index
The duration of venous blood damming of 2 minutes greatly affects the results of the examination, because it can cause the results of the examination to increase or decrease and damage the blood specimen. This study aims to determine the number of platelets from the results of the examination of the duration of venous blood sampling using 1 minute and 2 minutes. The method in this study used descriptive quantitative to do two treatments, namely the length of damming the venous blood collection using 1 minute (Normal) and 2 minutes (Abnormal). The results showed that routine blood tests were influenced by pre-analytical, analytical, and post-analytic factors. Among them are pre-analytic factors that affect routine blood, the duration of damming venous blood collection for 2 minutes greatly affects the results of the examination, because it can cause the results of the examination to increase or decrease and damage the blood specimen.
Hak Cipta (c) 2023 Fitriyanti Lauha, Yusri Halada, La Ode Sultan
DESCRIPTION OF ELECTROLYTE LEVELS IN PATIENTS DIABETES MELLITUS AT TOTO KABILA HOSPITAL KAB. BONE BOLANGO
This research aims to to know the description of electrolyte levels in patients with diabetes mellitus at Toto Kabila Hospital, Bone Bolango Regency. The method in this study uses a descriptive qualitative approach. The type of data used is data in the form of research results and secondary data in the form of data from literature, books, questionnaires, and medical records. The sampling technique in this study used a purposive sampling technique, totaling 23 samples. Results This study shows that the percentage of electrolyte level examination results in patients with diabetes mellitus from 23 respondents obtained the results of abnormal electrolyte levels examination 5 people (21.7%) and normal ones as many as 18 people (78.3%).
Overview of erythrocyte sedimentation rate examination results of farmers aged 30-40 years in Manunggal Karya Village Sub-district of Randangan District of Pohuwato
Pregnancy causes physical and emotional changes from pregnant women as well as social changes in the family. Pregnancy in general will continue to develop until a healthy baby is born through the birth canal. However, under certain conditions, sometimes the baby cannot be expelled through the birth canal. In this condition, a caesarean section is an alternative to remove the baby from the mother's stomach because normal delivery does not work and the baby does not come out after 20 hours than it should be. This can be caused by the size of the baby being too large against the birth canal, slowing of the cervical effacement or because the babies to be born are twins who are feared to slow down the birth process. This study aims to describe the results of the prothrombin time (PT) and activated partial thromboplastin time (APTT) examinations in pregnant women before surgery at the Bumi Panua Pohuwato Regional General Hospital, sub-district of Marisa, district of Pohuwato, province of Gorontalo. This research method used descriptive analysis with a quantitative approach. Sampling used an accidental sampling technique. The results showed that on the prothrombin time examination, 5 patients (16.7%) had abnormal PT results, while 25 patients (83.3%) had normal PT results. In the activated partial thromboplastin time examination using the same samples, 12 patients (40%) had abnormal APTT results and 18 patients (60%) had normal APTT results. The total sample was 30 pregnant women (100%).
PT, APTT, caesarean section, pregnant women
Hak Cipta (c) 2023 Niken Apriyani Abas, Rita Amini Warastuti, Titin Dunggio
This study aims to identify Candida sp in the urine of patients with diabetes mellitus at the Prof. Regional General Hospital. Dr. H Aloe Saboe, Gorntalo City. This type of research is qualitative using descriptive methods and data collection techniques, namely fungal culture examination, interviews and documentation. The sampling technique used in this study was purposive sampling, with a total of 10 people. Based on the results of the study, it was found that Candida albicans, Candida glabrata, Candida parasilopsis, Candida dubliniensis were found in culture media, Candida species were round, smooth, white-cream colored with shiny colonies, and the fungus Aspergilus fumigatus.
Hak Cipta (c) 2023 wahyunihasa hasan, Laksmyn Kadir, La Ode Sultan
This study aims to identify the presence or absence of borax and formalin in meatballs and wet noodles in Gorontalo City. The type of research used in this research is descriptive with a qualitative approach. Using the curcumin paper method (tumeric) to identify the borax content and the 0.1 N KMnO4 method (Potassium Permanganate) to identify the Formalin content. The sampling technique is purposive sampling and the data collection technique is based on the results of tests conducted in the laboratory. The data processing method goes through several stages, namely editing, coding, tabulating, data cleaning, data descrbing and data analysis, namely the number of presentation frequencies is calculated using the number formula for each sample of meatballs and wet noodles that are positive for borax and formalin divided by the total number of each sample of meatballs and wet noodles. The results of the research carried out can be concluded from the total sample of meatballs, namely 20 samples, 20 were negative Borax (0%) and 16 of them were Formalin positive (80%). while for the sample of wet noodles with a sample of 7, 6 positive results were obtained for Borax (85.71%) and 5 were positive for Foramalin (71.42%).
Hak Cipta (c) 2023 Putri Sri Widya Yadano, Adnan Malaha, Astria lolo
INFLUENCE OF Immersion Time Tofu IN SALT SOLUTION ON FORMALINE RESIDUE
Tofu is a food ingredient made from soybeans and contains a lot of nutritional value, so there are traders who use formalin as a preservative. Formalin is an efficient chemical additive, but is prohibited from being added to food (food). This study aims to determine the presence of formalin residues in tofu based on variations in salt solution soaking time. The research method used is experimental. Data obtained from the Test Kit Formaldehyda with two treatments based on the addition of formalin and salt solution. The treatments were: 1. P1 (6% formalin) and 2. P2 (6% salt solution). The results showed that from 32 samples of tofu soaked in salt solution 45 minutes, 60 minutes, 75 minutes and 90 minutes were tested using reagents A1 1 ml and A2 3 ml. It shows a decrease in formalin residue as much as 45.63%, 69.28%, 82.36% and 91.80%.
Soaking Time Tofu, Salt Solution, and Residue Formalin
Hak Cipta (c) 2023 Sri Sindayana Y. Tane
ANTIBACTERIAL TEST OF Basil (Ocimum sanctum) LEAF EXTRACT AND FRACTION ON Escherichia coli BACTERIA GROWTH
Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak dan fraksi daun kemangi dalam menghambat pertumbuhan bakteri Escherichia coli dan untuk mengetahui konsentrasi yang terbaik dalam menghambat pertumbuhan bakteri Escherichia coli. Metode dalam penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan lima perlakuan dan lima pengulangan berdasarkan masing-masing kelompok perlakuan ekstrak dan fraksi yaitu: konsentrasi 25%, konsentrasi 50% dan konsentrasi 75%. Hasil penelitian menunjukan bahwa dari masing-masing konsentrasi yang digunakan dari kelompok ekstrak dan fraksi didapatkan bahwa konsentrasi terbesar dalam menghambat bakteri Eschericia coli pada konsentrasi 75% kelompok ekstrak. Analisa data secara statistik menggunakan Metode Kruskal Wallis terdapat perbedaan nilai yang signifikan antara ekstrak dan fraksi sehingga dilanjutkan dengan menggunakan uji Post Huc Duncan. Kata Kunci : Kemangi, Ekstrak, Fraksi, Escherichia coli
EXT COMBINATION ACTIVITIES WHITE WOOD SHELF (Melaleucaleucadendra) AND HONEY AS NON-SPECIFIC IMUNOMODULATOR IN MALE WHITE RATS (Rattusnorvegicus)
Mita Kurniawati, 2120192043. 2021. The Combination of Eucalyptus Extract (Melaleuca leucadendra) and Honey as Non-Specific Immunomodulators in Male White Rats (Rattus norvegicus). Undergraduate Thesis, advisor I: Dr. Laksmyn Kadir, M.Kes., and advisor II: Apt. Moh. Taufik Ismullah, M.Farm. Bachelor of Pharmacy, Faculty of Science, Technology, and Health Sciences, Universitas Bina Mandiri Gorontalo. This study aims to find out the combination of eucalyptus leaf extract (Melaleuca leucadendra) and honey that can provide non-specific Immunomodulators activity in male white rats (Rattus norvegicus). The method in this study used quasi-experiments with a pretest-posttest approach that used test groups and comparison groups. The groups were: C1 (negative control), C2 (positive control), and C3 (test group). The results showed that three test groups of a combination of eucalyptus leaf extract (Melaleuca leucadendra) and honey can increase the levels of leukocytes in the blood that serve as Immunomodulators. Analysis of paired sample t-test statistical data where the significance value of P ≤ 0.05 showed that there was activity between a combination of eucalyptus (Melaleuca leucadendra) and honey to increase the levels of leukocytes in the blood that function as immunomodulators. Keywords: Immunomodulators, Honey, Leukocytes
FORMULATION OF LIPBALM FROM SARI MEAT PAPAYA FRUIT (Carica papaya L.) AS A PREPARATION SUNBLOCK
Sri Ainun Tahir, 2120192054. 2021. Formulasi Sediaan Lipbalm Dari Sari Daging Buah Papaya (Carica Papaya L.) Sebagai Sediaan Tabir Surya. Skripsi, Pembimbing I: Dr. Hj. Titin Dunggio., M.Si, M.Kes dan Pembimbing II: Gita Puspita, M.Farm. Program Studi S1 Farmasi, Fakultas Sains, Teknologi dan Ilmu Kesehatan. Penelitian ini bertujuan untuk mengetahui apakah sari daging buah pepaya dapat diformulasikan sebagai sediaan lipbalm, bagaimana stabilitas fisik sediaan dan apakah dapat berkhasiat sebagai tabir surya. Jenis penelitian ini menggunakan penelitian kuantitatif yang dilakukan secara eksperimental laboratorium dengan design penelitian yaitu simple random sampling. Hasil penelitian menunjukkan bahwa sari daging buah pepaya dapat diformulasikan sebagai sediaan lipbalm, formulasi sediaan lipbalm dengan konsentrasi 5%,7,5% dan 10% dapat berpengaruh pada stabilitas fisik sediaan dan sediaan lipbalm dari sari daging buah pepaya dengan konsentrasi 5% menghasilkan nilai SPF yaitu 5,912 memberikan perlindungan rendah,7,5% menghasilkan nilai SPF yaitu 7,841 memberikan perlindungan rendah dan 10% menghasilkan nilai SPF 12,591 memberikan perlindungan rendah. Berdasarkan hasil penelitian, maka dapat disimpulkan bahwa sediaan lipbalm yang dibuat dapat berkhasiat sebagai tabir surya tetapi memberikan perlindungan yang rendah. Kata kunci: Sari buah pepaya, Lipbalm, Tabir Surya
The purpose of this study was to compare the results of the examination and determine the factors that affect blood glucose levels while with fasting blood glucose levels in patients with diabetes mellitus at Toto Kabila Hospital. This research method uses a quantitative research approach with the type of research used in this study is an analytical observational research type. The population in this study were all patients with diabetes mellitus who had an examination. The sample used was 30 patients with a sampling technique using purposive sampling. The results of this study indicate that the factors that affect blood glucose levels during and fasting are age, obesity, genetic history and lifestyle, and there are differences in the results of the examination. fasting blood glucose and fasting blood glucose where the results of non-parametric analysis with a significant value (2-Tailed) that is .000 <0.05, from the results obtained the null hypothesis (H0) is rejected and the alternative hypothesis (Ha) is accepted.
Hak Cipta (c) 2023 Mita Putri Wahyudi, Erfan AR Lainjong, Titin Dunggio
HEPATITIS B SURFACE EXAMINATION PICTURE ANTIGENS ON CLEANING OFFICERS WORKING AT DUNDA LIMBOTO Hospital
This study aims to determine the results of hepatitis B examination on janitors at RSUD Dr. MM Dunda Limboto. The method in this study used a qualitative descriptive, immunochromatography method, focused on examining hepatitis B and identifying risks to the safety and health of janitors working at Dunda Limboto Hospital, Gorontalo Regency. The results showed that the examination of hepatitis b surface antigen on hospital cleaners, with a total sample of 14 serum samples using the HBsAg rapid test tool, the results obtained were 100 non reactive. Non-reactive results were obtained from the HBsAg rapid test tool, which only appeared a red line in the Control (C) area, while in the Test (T) area there was no red line. research results all samples (100%) Non Reactive. Suggestions for cleaners to be further improved in maintaining health and paying attention to safety when working, especially wearing personal protective equipment (masks, safe clothes, gloves, safe shoes if needed)
Hak Cipta (c) 2023 Ni Nyoman Eni Muliawati, Titin Dunggio
Hak Cipta (c) 2023 Nurain Rahman, Agusrianto Yusuf, Mindy Eka Astuti
Escherichia coli is a normal bacterial flora that is often found in the human intestine, is unique because it can cause primary infections such as diarrhea. This study aims to identify or see the presence or absence of Escherichia coli bacteria in fruit ice sold by street vendors in Gorontalo City. Methods in researchit uses a qualitative approach. The type of research used is descriptive observational where research on the presence of Escherichia coli bacteria is carried out on fruit ice drinks according to the results of laboratory tests carried out. The sampling technique used is random sampling and there are 8 locations of fruit ice sellers in Gorontalo City. Research result What has been done is that all samples that have been examined are not contaminated with Escherichia Coli bacteria but are contaminated or contaminated by other pathogenic bacteria.
EVALUATION OF COMPLIANCE WITH TUBERCULOSIS PATIENTS IN CONSUMING ANTI-TUBERCULOSIS MEDICINE (OAT) IN OUTPATIENT PATIENTS AT THE HEALTH CENTER WHEN
Penelitian ini bertujuan untuk mengetahui tingkat kepatuhan pasien, karakteristik pasien TB paru dan untuk mengetahui faktor yang mempengaruhi kepatuhan pada pasien rawat jalan di Puskesmas Kabila. Penelitian dilakukan dengan menggunakan pendekatan kuantitatif, Populasi dalam penelitian ini adalah seluruh pasien tuberculosis rawat jalan di Puskesmas Kabila sejumlah 28 orang teknik pengambilan sampel yang digunakan dalam penelitian ini adalah total sampling. penelitianini merupakan penelitian deskriptif yang dilakukan secara observasional dengan menggunakan instrumen penelitian yaitu, Formulir Informed Consentdan Kuesioner MMAS-8. Analisis data yang dilakukan menggunakan analisis data deskriptif. Hasil peneltian karakteristik pasien terdiri dari jenis kelamin, usia, pendidikan dan pekerjaan, pasien di puskesmas kabla memiliki tingkat kepatuhan yang tinggi dalam penggunaan obat untuk proses penyembuhan penyakit TB, hal tersebut dapat di lihat pada hasil penelitian di atas dimana tingkat kepatuhan pasien memperoleh kategori tinggi yaitu berjumlah 23 orang atau sebesar 82.14%% rendah 5 atau 17.85%. Kata Kunci: Kepatuhan, Tuberculosis, Mengkonsumsi OAT.
Compliance, Tuberculosis, Consuming OATS
Hak Cipta (c) 2023 Tia Fitria Tamrin, Ahmad Husain Palli, Atvinda Pirlya Afista
THE EFFECT OF CHILDREN (Ocimum sanctum) LEAF EXTRACT ON BACTERIA GROWTH Staphylococcus aureus
Penelitian ini bertujuan untuk mengetahui pengaruh ekstrak daun kemangi (Ocinum sanctum) terhadap pertumbuhan Staphylococcus aureus serta konsentrasi optimalekstrak daun kemangi (Ocinum sanctum) dalam menghambat pertumbuhan Staphylococcus aureus. Metode penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan 4 kali ulangan yang terdiri dari kontrol negative (aquades), kontrol positif (Amoxicillin), Ekstrak 20%, 40% dan 60%. Hasil penelitian diperoleh bahwa ekstrak daun kemangi (Ocinum sanctum) memiliki pengaruh terhadap pertumbuhan bakteri Staphylococcus aureus. Konsentrasi optimal ekstrak daun kemangi (Ocinum sanctum) dalam meghambat pertumbuhan bakteri Staphylococcus aureus yaitu pada konsentrasi 40% dengan kategori daya hambat bakteri “kuat”. Kata Kunci : Kemangi (Ocinum sanctum), Staphylococcus aureus, Ekstrak, Bakteri
Hak Cipta (c) 2023 Mohammad Andi Laboddu
IDENTIFICATION OF CORTICOSTEROID HARD DRUG CONTENT IN WHITENING COSMETIC PREPARATIONS CIRCULATING IN GORONTALO CITY
This study aims to identify the corticosteroids in whitening cosmetic preparations circulating in Gorontalo City. The method used in this study was thin layer chromatography (TLC), with a qualitative approach and a descriptive (observational) type of research. The results showed that identification in the UV laboratory at a wavelength of 254 nm showed that from the 5 cream samples and 5 lotion samples for whitening cosmetic preparations tested, four of them were positive for the strong drug class of corticosteroid betamethasone valerate, namely with an Rf value on (cream sample E 0, 91), (lotion sample A 0, 91), (lotion sample B 1.0), and (lotion sample C 1.0) and have Rf values identical or similar to standard Rf values under the same chromatographic conditions.
Corticosteroid, Whitening Cosmetic, Chromatography, Thin Layer.
THE ACTIVITY TEST OF BIDARA LEAF ETHANOL EXTRACT (ZIZIPHUS MAURITIANA) TOWARDS ESCHERICHIA COLI BACERIA
This research aims at investigating the antibacterial activity and optimum concentration of the ethanol extract of bidara leaves (Ziziphus mauritiana) against Escherichia coli bacteria. The method used in this research is a completely randomized design (CRD) consisting of 7 treatments and 4 replicates. The treatments are: P1 (negative control Aquades), P2 (10% concentration), P3 (12.5% concentration), P4 (15% concentration), P5 (17.5% concentration), P6 (20% concentration), and P7 (positive control Ciprofloxacin). The findings reveal that the concentration of ethanol extract of bidara leaves (Ziziphus mauritiana) has activity in inhibiting the growth of Escherichia coli bacteria. From the results of Kruskall-Wallis statistical analysis with a significant value of 0.003 or < 0.05, it appears that there is a dose of ethanol extract of bidara leaves (Ziziphus mauritiana) that affects the growth of Escherichia coli bacteria. After further testing (Duncan test), it was found that there was no significant difference between one concentration and another, so it can be said that the optimum concentration of bidara leaf ethanol extract treatment (Ziziphus mauritiana) in inhibiting the growth of Escherichia coli bacteria is at a concentration of 10%.
Bidara leaf ethanol extract (Ziziphus mauritiana), Antibacterial Activity, and Escherichia coli Bacteria